Wipe beef well. Combine 1/3 cup flour with salt and pepper. Toss beef cubes with flour mixture to coat thoroughly; place in crockpot. Add remaining ingredients except 2 tb. flour and the water in order listed; stir well.
Cover and cook on Low setting for 7 to 12 hours. One hour before serving, turn to High setting. Make a smooth paste of 2 tb. flour and the water; stir into crockpot, mixing well. Cover and cook until thickened.